to cause (a person) to become unfriendly or indifferent (by unpopular or unpleasant actions)

cause unfriendliness, hostility

to make (a person) bed-tempered

irritate, upset

to discourage or prevent a person

check, inhibit from action

to annoy or offend (a person); make (a person) angry

make unhappy

to advise a person against (doing something)

talk out of

to cause a person no longer to have friends

destroy the affections of

to annoy, cause distress in, (a person)

distress, bother